Ann Pharmacother 33 (1999): 172-4, 74. Clin Nephrol 27 (1987): 161-2, 29. Microzide (hydrochlorothiazide) is a diuretic used to treat excessive fluid accumulation and swelling (edema) of the body caused by heart failure, cirrhosis, chronic kidney failure, corticosteroid medications, and nephrotic syndrome. Ann Surg 163 (1966): 291-6, 67. However, if you experience any of the symptoms of serious side effects listed above, seek medical attention immediately. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Severe stomach pain 2. The eruption resolved upon discontinuation of HCTZ, but she later developed a higher ANA titer associated with symptomatic diffuse interstitial pulmonary infiltrates. Sexual Problems 8. You may report side effects to the FDA at 1-800-FDA-1088. Available for Android and iOS devices. Ann Intern Med 122 (1995): 223-6, 26. Ann Pharmacother 29 (1995): 701-3, 53. Hydrochlorothiazide (HCTZ or HCT) is a diuretic medication often used to treat high blood pressure and swelling due to fluid build up. It is typically reversible within six months after discontinuation of therapy. Dizzy 4. muscle cramps. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). N Engl J Med 321 (1989): 868-73, 5. Berlin I "Prazosin, diuretics, and glucose intolerance." Ann Intern Med 122 (1995): 133-41, 31. Treatment with metoprolol, propranolol and hydrochlorothiazide." Hyperuricamia may be an important consideration in patients with a history of gout. Staci Eastin has been a licensed pharmacist for 14 years. Acta Med Scand 221 (1987): 143-8, 3. Signs of an allergic reaction include hives, breathing or swallowing difficulties and swelling of the face or throat. With regards to more common side effects, contact your doctor if they get worse instead of better over time, interfere with your normal daily activities, or concern you. Losartan/hydrochlorothiazide can cause mild or serious side effects. Hydrochlorothiazide belongs to a group of drugs called diuretics ("water pills"), which help the body get rid of excess fluid. Rosenberg L, Shapiro S, Slone D, Kaufman DW, Miettinen OS, Stolley PD "Thiazides and acute cholecystitis." Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Stomach upset, headache, frequent urination, electrolyte imbalance, and dizziness are some of the most common side effects of this medication. Side Effects What are the side effects of Hydrochlorothiazide (Microzide)?. Murphy MB, Kohner E, Lewis PJ, Schumer B, Dollery CT "Glucose intolerance in hypertensive patients treated with diuretics: a fourteen-year follow-up." N Y State J Med 72 (1972): 1741-2, 30. Feel Like Throwing Up 9. Am J Surg 112 (1966): 97-101, 71. Photodermatol 6 (1989): 100-2, 61. Abnormally Low Blood Pressure 2. Hollifield JW, Slaton PE "Thiazide diuretics, hypokalemia and cardiac arrhythmias." These side effects may go away during treatment as your body adjusts to the medicine. This content does not have an English version. Drugs.com. Medically reviewed by Drugs.com. Pollare T, Lithell H, Berne C "A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension." Goette DK, Beatrice E "Erythema annulare centrifugum caused by hydrochlorothiazide-induced interstitial nephritis." Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Muscle weakness 2. South Med J 79 (1986): 1456-7, 2. Goodrich AL, Kohn SR "Hydrochlorothiazide-induced lupus erythematosus: a new variant?" We want to hear success stories as well as tales of woe and intrigue. High Blood Sugar 3. In some cases, doses as small as 12.5 mg were associated with the development of pulmonary edema. If experienced, these tend to have a Severe expression 1. The combination of lisinopril and hydrochlorothiazide is used to treat high blood pressure. Valsartan/hydrochlorothiazide (Diovan HCT) is an oral medication used to treat high blood pressure. Stomach Cramps 11. J Am Acad Dermatol 28 (1993): 1001-2, 58. Stomach upset, headache, frequent urination, electrolyte imbalance, and dizziness are some of the most common side effects of this medication. Rechallenge can result in a more severe reaction, even months to years after the initial exposure. Hydrochlorothiazide has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. Chest Pain 4. Holland GW "Stenosing ulcers of the small bowel associated with thiazide and potassium therapy." Common side effects may include: nausea, vomiting, loss of appetite; Along with its needed effects, hydrochlorothiazide may cause some unwanted effects. 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